What’s NMN?
NMN is brief for nicotinamide mononucleotide, a natural molecule seen in all species. On the molecular level, it is just a ribonucleotide, a fundamental structural unit from the nucleic acid RNA. It consists of a nicotinamide group, a ribose, plus a phosphate group.
NMN is a precursor of nicotinamide adenine dinucleotide (NAD+), a molecule which might be useful in slowing down some facets of aging. NAD+ serves many critical functions inside our cells, such as electron transport, cell signaling, and DNA repair.
Accumulating evidence suggests that as our bodies age, our levels of NAD+ decline, increasing our likelihood of age-related diseases.
This is how the NAD+ precursor NMN comes in. Some researchers feel that when we can restore that lost NAD+, we’re able to not only slow down aging and also delay various age-related diseases. If restoring NAD+ metabolism in humans will slow aging or support healthy longevity remains an unanswered question, although the animal information is promising.
What foods contain NMN?
NMN can be found naturally in foods such as avocado, broccoli, cabbage, cucumber, and edamame. This is one way much NMN is found in some common foods.
While these kinds of foods are full of nutrition, dietary NMN supplements can be found. These supplements typically come in doses which is between 100 – 500 mg, although an optimal dose has to be determined in people.
Fasting and caloric restriction also seem to increase NAD+ levels and boost the activity of sirtuins, aka the longevity genes. It is suggested the activity utilizes the presence of NAD+. In mice, fasting boosted NAD+ levels and sirtuin activity, also it seems to decrease aging.
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